Shengyuan Peptides

Catalog / GH Axis Peptides / IGF-1 LR3

IGF-1 LR3 research peptide — GH Axis Peptides

IGF-1 LR3

Long-acting insulin-like growth factor 1 analogue used to investigate growth-factor signaling, cell proliferation, and anabolic pathways in research systems.

CAS Number946870-92-4
Molecular Weight9117.5 Da
Purity99.2% (HPLC / MS verified)
CategoryGH Axis Peptides
Quality metricsHPLC purity, peptide content, and identity are reported separately on the batch COA — see the purity guide.
StorageStore lyophilized IGF-1 LR3 at -20°C in a desiccated, light-protected environment; avoid mechanical agitation of stock solutions.
Research use only. Not for human or veterinary use. We do not provide dosing guidance or medical advice.
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About IGF-1 LR3

IGF-1 LR3 is an 83-amino-acid analogue of human insulin-like growth factor 1 engineered with a glutamic-acid-to-arginine substitution at position 3 and a 13-residue N-terminal extension. These modifications weaken binding to IGF-binding proteins and prolong the peptide's availability in culture and preclinical systems, making LR3 a preferred reagent when sustained IGF-1 receptor activation is required. Investigators use it to study IGF-1R signaling cascades, PI3K/Akt and MAPK pathway activation, myoblast proliferation and differentiation, and growth-factor biology in cell and tissue models. Given its size and disulfide architecture, quality control must confirm correct folding alongside purity: misfolded isomers, truncated chains, and methionine oxidation can all alter receptor engagement without being resolved by simple HPLC. Shandong Shengyuan validates IGF-1 LR3 by RP-HPLC purity of 99.2% or higher, LC-MS mass confirmation, and functional reference data, and ships each lot lyophilized with a certificate of analysis. For research use only; not for human or veterinary use.

Research Applications

  • IGF-1R signaling studies
  • Myoblast proliferation assays
  • PI3K/Akt pathway research
  • Growth-factor cell culture work
  • Muscle biology models

Quality & Documentation

Every batch of IGF-1 LR3 is manufactured under our documented quality system and released with a Certificate of Analysis covering HPLC purity, mass spectrometry identity, peptide content, water content, and endotoxin. The batch code on your vial can be verified online in the COA lookup section of this site.

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